if you are zerg, you have several options, you may use defiler+hydra+zergling(as defilers meal), or, you can use plague+few devourers+mass mutas+some scourges(only if you are good at controling).
if you are terran, you can shake them with emp first, then clock them down(hard control, most important), then marines+"shah! that's the stuff!". if you are bad at controling, don' use marines, wraiths and goliaths will do full damage to cuisers.
if you are protoss, best is freeze them up, because they are usually close to each other. than gather scouts and high templars. when they are defrozen quickly make some psionic storms.
actually good terran players will send cruisers with other units, so most importand is patroling and to find his intention as early as possible.