it might be the blood golem thats getting you killed, it shares damage taken with your own hit pool.
use the clay golem instead, your skeletons will only be as useful as long as they are alive, so make sure you have a good set of them. try for cold mages so he slows down and damage comes at a slower rate. if all your skeletons die, try opening a tp and getting some more, then rinse and repeat, he should eventually fall. dont try to run in and help at a close range, duriel will do lots of damage to you and you could die. try using ranged attacks, or magic,and use any curse you have
you might also want to consider playing online if your single player. even if you like to play solo, if you do find you just simplely can't beat a certain boss, you can join a game solely to get help from your peers with that, then go back to playing in a private game.you will however, have to restart your character. thats just a suggestion though, if you enjoy playing single player, go right ahead, lots of people prefer it to online play.